Usual Pathogens
Coagulase negative Staph
S. aureus/MRSA
Enterobacterales
Group B Streptococci
| Empiric Therapy | Duration | |
|---|---|---|
| Cloxacillin | 200mg/kg/d IV div q6h | ≥ 7 days |
| + | ||
| Gentamicin | 4-5mg/kg IV q24h |
If post op heart surgery, central venous line or very low birth weight or high institutional MRSA rate
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 45mg/kg/d IV div q8h | ≥ 7 days |
| + | ||
| Gentamicin | 4-5mg/kg IV q24h |
Severely ill
| Empiric Therapy | Duration | |
|---|---|---|
| Vancomycin | 45mg/kg/d IV div q8h | ≥ 7 days |
| + | ||
| Meropenem | 60-90mg/kg/d IV div q8h |