Pantoea spp

• P. agglomerans
• P. calida
• P. gaviniae
• P. septica

• Gram negative bacilli - fermenter

Clinical Significance

These organisms are widely distributed in the environment including soil and vegetation.

They have been associated with skin, soft tissue, bone and joint infections typically after penetrating trauma by contaminated objects.

Bacteremias are often polymicrobial.

They can cause healthcare related infections (including outbreaks), involving contaminated fluids.

When co-isolated with other organisms, their significance is questionable.

Usual Susceptibility Pattern

These organisms produce an inducible chromosomal cephalosporinase (Amp C) and are resistant to ampicillin, amoxicillin +/- clavulanate, and 1st/2nd generation cephalosporins. 

Although typically susceptible in vitro to 3rd generation cephalosporins, use of these agents may result in selection of resistant strains.

Pantoea spp are usually susceptible to aminoglycosides, quinolones, and TMP/SMX.