Rothia spp

• Rothia kristinae
• R. dentocariosa
• R. mucilaginosa

• Gram positive cocci (aerobic)

Clinical Significance

These organisms are part of the commensal oropharyngeal flora.

R. dentocariosa - implicated in dental caries and periodontal disease as well as endocarditis and pneumonia in immunocompromised patients.

R. mucilaginosa (formerly Stomatococcus mucilaginosus) - associated with septicemia, endocarditis, meningitis, pneumonia, peritonitis, medical device related, skin, soft tissue, bone and joint infections, typically in immunocompromised or debilitated patients.

Usual Susceptibility Pattern

These organisms are usually susceptible to ampicillin (better activity than penicillin), cephalosporins, and tetracyclines,

Despite in vitro susceptibility to vancomycin, clinical failures have been described.

Susceptibility to clindamycin and macrolides is variable. 

In serious infections, addition of gentamicin should be considered.