Meningitis: Adults 18-50 years AND Immunocompetent
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 2g IV q12h | See Duration |
| + | ||
| Vancomycin | 25-30mg/kg IV once then 15mg/kg IV q8-12h |
Cephalosporin allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Meropenem | 2g IV q8h | See Duration |
| + | ||
| Vancomycin | 25-30mg/kg IV once then 15mg/kg IV q8-12h |
Carbapenem allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| [TMP/SMX | 15-20mg TMP/kg/day IV div q6-8h | See Duration |
| or | ||
| Ciprofloxacin] | 400mg IV q12h | |
| + | ||
| Vancomycin | 25-30mg/kg IV once then 15mg/kg IV q8-12h |