Rubella
Potential Effect on Fetus
- Fetal loss
-
Congenital Syndrome especially:
- hearing loss
- congenital heart failure
- cataracts
- thrombocytopenia/purpura
Rate of Perinatal Transmission
- 1st trimester – 67-85% (infection in 1st trimester associated with more severe fetal infection)
- 11-16 weeks – 55%
- > 16 weeks – 45%
Maternal Screening
- Routine Rubella IgG performed in 1st trimester.
- If maternal rubella suspected, perform Rubella IgM.
Prevention
- Vaccination before or after pregnancy (not during).
- In acute infection – droplet precautions.
- In neonatal infection acquired congenitally, use contact precautions for at least 1 year unless nasopharyngeal and urine cultures repeatedly negative after 3 months.