Otogenic (otitis, mastoiditis)
Usual Pathogens
Polymicrobial:
Streptococcus spp
S. aureus
H. influenzae
Anaerobes
Enterobacterales
P. aeruginosa
| Empiric Therapy | Duration | |
|---|---|---|
| Surgical drainage | ||
| + | ||
| Piperacillin-tazobactam | 4.5g IV q6h | 14-21 days |
| or | ||
| Meropenem | 2g IV q8h |
14-21 days |
| If MRSA risk factors, add: | ||
| Vancomycin | 14-21 days |