Prior to genitourinary procedures in which mucosal bleeding/trauma is expected
- Pre-procedure cultures should be taken.
Usual Pathogens
E. coli
Other Enterobacterales
Enterococcus spp
Prophylactic regimens (base on C&S results)
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefixime | 400mg PO | single dose 1-2 hours pre-op |
| or | ||
| Ciprofloxacin | 500mg PO | single dose 1-2 hours pre-op |
| or | ||
| Norfloxacin | 400mg PO | single dose 1-2 hours pre-op |
| or | ||
| TMP/SMX | 1 DS tab PO | single dose 1-2 hours pre-op |
| or | ||
| [Gentamicin | 1.5mg/kg IV/IM | single dose |
| +/- | ||
| Ampicillin] | 1g IV/IM | single dose |