Staphylococcus spp, cloxacillin-susceptible
If staphylococcal hardware infection, add rifampin (after clearance of bacteremia). With implants, often need lifelong suppressive therapy.
If no debridement, consider adding rifampin (after clearance of bacteremia) and continue therapy for minimum 12 weeks.
| Therapy | Dose | Duration |
|---|---|---|
| Cloxacillin | 2g IV q4h | 6 weeks |
| or | ||
| Cefazolin | 2g IV q8h | 6 weeks |
Cloxacillin & cefazolin allergy
| Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 15mg/kg IV q8-12h | 6 weeks |