Initial episode
Usual Pathogens
Clostridioides (Clostridium) difficile
Mild-moderate
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Metronidazole | 30mg/kg/d PO div qid (max 500mg PO qid) | 10-14 days |
Severe/unresponsive to metronidazole
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 40mg/kg/d PO div qid (max 125mg PO qid) | 10-14 days |