Trimethoprim-Sulfamethoxazole (TMP/SMX)

Predictable Activity

Actinobacillus spp
Actinobaculum spp
Acinetobacter spp
Actinotignum spp
Achromobacter spp
Aerococcus spp (other than A. urinae)
Aggregatibacter spp
Alcaligenes spp
Bordetella bronchoseptica
Brevundimonas spp
Coagulase negative Staphylococci (CoNS)
Comamonas spp
Eikenella corrodens
Enterobacter spp
Klebsiella oxytoca
Klebsiella pneumoniae
Moraxella catarrhalis
Neisseria spp (other than N. gonorrhoeae)
Ochrobactrum spp
Oligella spp
Pasteurella spp
Plesiomonas spp
Pseudomonas spp (other than P. aeruginosa)
Ralstonia spp
Serratia spp
Shewanella spp
Shingobacterium spp
Staphylococcus aureus (MSSA, MRSA)
Staphylococcus lugdunensis
Stenotrophomonas maltophilia
Weeksella spp

Unpredictable Activity

Actinobaculum spp
Aeromonas spp
ß-haemolytic Streptococci (Group A,B,C,G)
Bergeyella spp
Burkholderia spp
Capnocytophaga spp (canine source)
Campylobacter spp
Chryseobacterium spp
Citrobacter freundii complex
Corynebacterium spp
Coryneform bacteria
Escherichia coli
Haemophilus influenzae
Haemophilus parainfluenzae
Kingella spp

Listeria monocytogenes
Morganella morganii
Nocardia spp
Proteus mirabilis
Proteus vulgaris complex
Providencia spp
Rhizobium spp
Rhodococcus equi
Salmonella spp
Shigella spp
Streptococcus pneumoniae
Viridans group Streptococci

No/Insufficient Activity

Aerococcus urinae
Arcanobacterium haemolyticum
Bacillus spp
Bordetella pertussis
Capnocytophaga spp (human source)
Enterococcus spp
Erysipelothrix rhusiopathiae
Gardnerella vaginalis
Helicobacter pylori
Neisseria gonorrhoeae
Pseudomonas aeruginosa
Roseomonas spp
Trueperella spp