Bacterial - Hyperacute
- Usually unilateral with a fulminant onset (< 24 hours)
- Copious purulent discharge, conjunctival hyperemia, redness, and irritation. Preauricular lymphadenopathy commonly seen.
- Corneal perforation can occur in up to 10% of cases. Refer to an ophthalmologist promptly.
- Obtain Gram stain and culture of conjunctival scrapings.
- Consider adjunctive topical antibiotic therapy (bacitracin-polymyxin or erythromycin).
Usual Pathogens
N. gonorrhoeae
N. meningitidis
Empiric Therapy | Dose | Duration |
---|---|---|
Ceftriaxone | 2g IV/IM | 1 dose |
+ | ||
[Azithromycin | 1g PO | 1 dose |
or | ||
Doxycycline] | 100mg PO bid | 7 days |
Severe cephalosporin allergy
Empiric Therapy | Dose | Duration |
---|---|---|
Ciprofloxacin | 500mg PO | 1 dose |
+ | ||
[Azithromycin | 1g PO | 1 dose |
or | ||
Doxycycline] | 100mg PO bid | 7 days |