Fusariosis
[Lancet Infect Dis 2021;21:e246-57]
Usual Pathogens
Fusarium solani species complex
Fusarium oxysporum species complex
Fusarium fujikuroi species complex
Fusarium incarnatum-equiseti species complex
Fusarium chlamidosporum species complex
Fusarium dimerum species complex
Fusarium sporotrichoides species complex
- Fluconazole and echinocandins have no activity against Fusarium species.
- Infectious Diseases consult recommended.
| Empiric Therapy | Duration | |
|---|---|---|
| Voriconazole |
6mg/kg IV/PO bid x 2 doses, then 4mg/kg IV/PO bid |
Treat until all signs and symptoms of the infection have resolved, radiographic abnormalities have stabilized, and significant immune reconstitution has occurred. |
| + | ||
| Amphotericin B, lipid complex or liposomal | 5mg/kg IV daily |