S. aureus, methicillin susceptible (MSSA)
| Empiric Therapy |
Intermittent Dosing 1 exchange daily with dwell time at least 6h |
Continuous Dosing (per each L bag) |
Duration |
|---|---|---|---|
| Cefazolin IP | 15-20mg/kg once per day | 500mg/L LD then 125mg/L MD |
21 days Treat for 14 days after catheter removal. |
| +/- | |||
| Rifampin PO |
450mg PO daily if weight <50kg, 600mg PO daily if weight ≥50kg |
450mg PO daily if weight <50kg, 600mg PO daily if weight ≥50kg |
|
| Paediatric: 10-20mg/kg/d PO div bid |
IP = intraperitoneally
LD = loading dose
MD = maintenance dose