Open or laparoscopic procedures with placement of prosthetic material
(penile implant, artificial sphincters)
Note: If positive urine culture pre-operatively, institute treatment according to culture and susceptibility results.
Common Pathogens
Enterobacterales
Enterococcus spp
Staphylococcus spp
Streptococcus spp
| Regimen(s) of Choice See General Principles and Pre-Op Antibiotic Administration and Intraoperative Antibiotic Administration | ||
|---|---|---|
| Cefazolin | 2g IV | x 1 pre-op dose |
| +/- | ||
| Gentamicin | 1.5mg/kg IV | x 1 pre-op dose |
| Alternative Regimens if allergy to cefazolin, or severe non-IgE-mediated reaction to any β-lactam (interstitial nephritis, hepatitis, hemolytic anemia, serum sickness, severe cutaneous reactions [e.g. SJS, TEN, DRESS]) | ||
|---|---|---|
| Vancomycin | 15mg/kg IV | x 1 pre-op dose |
| + | ||
| Gentamicin | 1.5mg/kg IV | x 1 pre-op dose |