S. lugdunensis
- Increased risk of perivalvular extension and metastatic infection. Early surgical intervention required.
| Therapy | Dose | Duration |
|---|---|---|
| Cloxacillin | 2g IV q4h | 6 weeks |
| or | ||
| Cefazolin | 2g IV q8h | 6 weeks |
| Severe penicillin allergy/anaphylaxis | ||
| Vancomycin | 15mg/kg IV q8-12h | 6 weeks |