Uncomplicated:

  • cholecystitis

  • diverticulitis

  • appendicitis

  • peritonitis

Empiric Therapy Dose Duration
Ceftriaxone 2g IV daily 5-10 days
+    
Metronidazole 500mg IV/PO q12h  

Cephalosporin allergy

Empiric Therapy Dose Duration
Ciprofloxacin 400mg IV q12h/500mg PO bid 5-10 days
+    
Metronidazole 500mg IV/PO q12h