Community-acquired or Nursing home-acquired with risk factors for anaerobes
- poor oral hygiene
- severe periodontal disease
- putrid sputum
S. pneumoniae
H. influenzae
S. aureus
Enterobacterales
Oral anaerobes
Streptococcus spp
Eikenella corrodens
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amoxicillin-clavulanate | 875mg PO bid | 5-7 days |
| or | ||
| [Ceftriaxone | 1-2g IV daily | 5-7 days |
| + | ||
| Metronidazole IV/PO] | 500mg IV/PO q12h |
Alternative
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Levofloxacin | 750mg PO daily | 5-7 days |
| + | ||
| Metronidazole IV/PO | 500mg IV/PO q12h |