Acute - Herpes Simplex I
Immunocompetent
Primary
| Empiric Therapy | Dose/Duration |
|---|---|
| Valacyclovir | 500mg-1g PO bid x 7 days |
| or | |
| Famciclovir | 500mg PO bid x 7 days |
| or | |
| Acyclovir | Adult: 400mg PO tid x 7 days |
| Paediatric: 40-60mg/kg/d PO div 4-5x/d |
Recurrent
| Empiric Therapy | Dose/Duration |
|---|---|
| No therapy indicated |
Immunocompromised
| Empiric Therapy | Dose/Duration |
|---|---|
| Valacyclovir | 500mg-1g PO bid x 7-10 days |
| or | |
| Famciclovir | 500mg PO bid x 7-10 days |
| or | |
| Acyclovir | 400mg PO 5x/day x 7-10 days |