Cephalexin

Predictable Activity

ß-haemolytic Streptococci (Groups A,B,C,G)
Staphylococcus aureus (MSSA)
Staphylococcus lugdunensis

Unpredictable Activity

Escherichia coli (for lower urinary tract infection only)
Proteus mirabilis (for lower urinary tract infection only)
Streptococcus pneumoniae (Pen-S)
Viridans group Streptococci

No/Insufficient Activity

Actinomyces spp
Aerobic Gram negative bacilli – nonfermenters
Anaerobic Gram negative bacilli
Bacillus spp
Bordetella spp
Capnocytophaga spp
Chlamydia spp
Citrobacter freundii complex
Corynebacterium spp
Eikenella spp
Enterobacter spp
Enterobacterales with ESBL or carbapenemase
Enterococcus spp
Haemophilus influenzae
Haemophilus parainfluenzae
Klebsiella oxytoca
Klebsiella pneumoniae
Legionella spp
Listeria monocytogenes
Moraxella catarrhalis
Morganella morganii
Mycoplasma spp
Nocardia spp
Pasteurella spp
Proteus vulgaris complex
Providencia spp
Pseudomonas aeruginosa
Pseudomonas spp
Salmonella spp
Serratia spp
Shigella spp
Staphylococcus aureus (MRSA)
Stenotrophomonas maltophilia
Streptococcus pneumoniae (Pen-I, Pen-R)
Yersinia spp