Imipenem
Predictable Activity
Actinomyces spp
Alcaligenes spp
Anaerobes (Gram positive and Gram negative)
ß-haemolytic Streptococci (Group A,B,C,G)
Bacillus spp
Burkholdenia spp (other than B. cepacia)
Cardiobacterium hominis
Citrobacter spp
Eikenella corrodens
Enterobacter spp
Escherichia coli
Haemophilus influenzae
Haemophilus parainfluenzae
Kingella kingae
Klebsiella oxytoca
Klebsiella pneumoniae
Leuconostoc spp
Moraxella catarrhalis
Neisseria spp
Pasteurella spp
Pediococcus spp
Pseudomonas aeruginosa
Raoultella spp
Salmonella spp
Serratia spp
Shigella spp
Staphylococcus aureus (MSSA)
Staphylococcus lugdunensis
Streptococcus pneumoniae (Pen-S, Pen-I)
Viridans group Streptococci
Unpredictable Activity
Acinetobacter spp
Aerobic Gram negative bacilli – nonfermenters
Aeromonas spp
Corynebacterium spp
Enterococcus faecalis
Morganella morganii
Mycobacterium spp
Nocardia spp
Plesiomonas spp
Proteus spp
Providencia spp
Pseudomonas spp (other than P. aeruginosa)
Streptococcus pneumoniae (Pen-R)
No/Insufficient Activity
Burkholderia cepacia
Chlamydia spp
Chryseobacterium spp
Elizabethkingia meningosepticum
Enterobacterales with carbapenemase
Enterococcus faecium
Legionella spp
Listeria monocytogenes
Mycoplasma spp
Staphylococcus aureus (MRSA)
Stenotrophomonas maltophilia