< 4 exacerbations/year and at least 2 of the following criteria:
- ↑ sputum volume
- ↑ sputum purulence
- ↑ dyspnea
Haemophilus spp
S. pneumoniae
Moraxella catarrhalis
First line agents
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amoxicillin | 1g PO tid | 5-7 days |
| or | ||
| Doxycycline | 200mg PO once, then 100mg PO bid | 5-7 days |
| or | ||
| TMP/SMX | 1 DS tab PO bid | 5-7 days |
Failure of first line agents
See ≥ 4 exacerbations/year and at least 2 of the following criteria: