Post trauma / Post neurosurgery
Usual PathogensS. aureus
Enterobacterales
P. aeruginosa
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Meropenem | 2g IV q8h | 6-8 weeks |
| + | ||
| Vancomycin | 15mg/kg IV q8-12h |
Carbapenem allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ciprofloxacin | 400mg IV q8-12h | 6-8 weeks |
| + | ||
| Metronidazole | 500mg IV/PO q8h | |
| + | ||
| Vancomycin | 15mg/kg IV q8-12h |