Impetigo

Superficial non-follicular pustules

- No evidence that disinfecting solutions are of any value.

 
Usual Pathogens
   Bullous
   
S. aureus
   Nonbullous, honey crust lesions
   Group A Streptococci

Limited involvement/disease

Empiric Therapy Dose Duration
Mupirocin 2% tid topically until resolved (max 7 days)
or    
Fusidic acid 2% tid-qid topically until resolved (max 7 days)

Unresponsive to topical or indication for systemic antibiotic

Empiric Therapy Dose Duration
Cloxacillin 40-50mg/kg/d PO div qid until resolved (max 7 days)
or    
Cephalexin 40mg/kg/d PO div qid until resolved (max 7 days)

ß-lactam allergy

Empiric Therapy Dose Duration
Erythromycin 40mg/kg/d PO div qid until resolved (max 7 days)
or    
Clindamycin 20mg/kg/d PO div qid until resolved (max 7 days)