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Antimicrobial Prophylaxis in Dentistry

  1. Addy M, Renton-Harper P.  Local and systemic chemotherapy in the management of periodontal disease: an opinion and review of the concept.  J Oral Rehabil 1996;23:219-31.
  2. American Academy of Orthopaedic Surgeons.  Antibiotic prophylaxis for bacteremia in patients with joint replacements.  AAOS June 2010.
  3. American Association of Endodontists.  Antibiotic prophylaxis quick reference guide.  Oct 1997.
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  5. American Urological Association and American Academy of Orthopaedic Surgeons.  Antibiotic prophylaxis for urological patients with total joint replacements.  J Urology 2003;169:1796-7.
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  27. Field EA, Martin MV.  Prophylactic antibiotics for patients with artificial joints undergoing oral and dental surgery: necessary or not? Br J Oral Maxillofac Surg 1991;29:341-6.
  28. Friedlander AH, Yoshikawa TT.  Pathogenesis, management, and prevention of infective endocarditis in the elderly dental patient.  Oral Surg Oral Med Oral Pathol 1990;69:177-81.
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  30. Gill AS, Morrissey H, Rahman A.  A systematic review and meta-analysis evaluating antibiotic prophylaxis in dental implants and extraction procedures.  Medicina 2018;54:95. https://doi:10.3390/medicina54060095.
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  36. Hupp JR.  Changing methods of preventing infective endocarditis following dental procedures: 1943-1993.  J Oral Maxillofac Surg 1993;51:616-23.
  37. Jacobson JJ, Schweitzer S, DePorter DJ, et al.  Antibiotic prophylaxis for dental patients with joint prostheses?  A decision analysis.  Int J Technol Assess Health Care 1990;6:569-87.
  38. Jacobson JJ.  Is the jaw bone connected to the hip bone?  Oral Surg Oral Med Oral Pathol: 263.
  39. Kashani H, Hilon J, Rasoul MH, et al.  Influence of a single preoperative dose of antibiotics on the early implant failure rate. A randomized clinical trial.  Clin Implant Dent Relat Res 2019;21:278–83.
  40. Katoh H, Sasaki J.  Clindamycin, its status as an antimicrobial agent in dentistry and oral surgery.  Oral Ther Pharmacol 1992;11:105-11.
  41. Khouly I, Braun RS, Chambrone L.  Antibiotic prophylaxis may not be indicated for prevention of dental implant infections in healthy patients. A systematic review and meta-analysis.  Clin Oral Invest 2019;23:1525–53.
  42. Khouly I, Braun RS, Silvestre T, et al.  Efficacy of antibiotic prophylaxis in intraoral bone grafting procedures: a systematic review and meta-analysis.  Int J Oral Maxillofac Surg 2020;49:250–63.  https://doi.org/10.1016/j.ijom.2019.07.003.
  43. Kotze MJ.  Antibiotic prophylaxis for preventing endocarditis and infection in joint prosthesis after dental treatment:  a review of new trends and recommendations in the literature.  SADJ 2008;63:440-4.
  44. Kotze MJ.  Prosthetic joint infection, dental treatment and antibiotic prophylaxis.  Orthopedic Reviews 2009;1:e7-9.
  45. Lancefield M, Conill AM.  Antibiotic prophylaxis.  Hosp Pract 1992;3:126-9.
  46. Little JW, Rhodus NL.  Dental treatment of the liver transplant patient.  Oral Surg Oral med Oral Pathol 1992;73:419-26.
  47. Little JW.  Antibiotic prophylaxis for prevention of bacterial endocarditis and infections of major joint prostheses.  Curr Opin Dent 1992;2:93-101.
  48. Little JW.  Managing dental patients with joint prostheses.  JADA 1994;125:1374-8.
  49. Little JW.  Preventing bacterial infections: managing the patient with cardiac defects, implants.  Dent Teamwork 1994;May-June:28-32.
  50. Lockhart PB, Loven B, Brennan MT, et al.  The evidence base for the efficacy of antibiotic prophylaxis in dental practice.  J Am Dent Assoc 2007;138:458-74.
  51. Lockhart PB, Schmidtke MA.  Antibiotic considerations in medically compromised patients.  Dent Clin North Am 1994;38:381-402.
  52. Longman LP, Martin MV.  The use of antibiotics in the prevention of post-operative infection: a re-appraisal.  Br Dent J 1991;170:257-62.
  53. Menon RK, Gopinath D, Li KY, et al.  Does the use of amoxicillin/amoxicillin–clavulanic acid in third molar surgery reduce the risk of postoperative infection? A systematic review with meta-analysis.  Int J Oral Maxillofac Surg 2019;48:263–73. https://doi.org/10.1016/j.ijom.2018.08.002.
  54. Meskin LH.  Focal infection: back with a bang!  JADA 1998;129:8-16.
  55. Milic T, Raidoo P, Gebauer D.  Antibiotic prophylaxis in oral and maxillofacial surgery: a systematic review.  Br J Oral Maxillofac Surg 2021.  https://doi.org/10.1016/j.bjoms.2020.09.020.
  56. Naimi-Akbar A, Hultin M, Klinge A, et al.  Antibiotic prophylaxis in orthognathic surgery:  a complex systematic review. PLoS ONE 2018;13:e0191161.  
  57. Newman HN.  Focal infection. J Dent Res 1996; 75: 1912-9.
  58. Newman MG.  The role of infection and anti-infection treatment in regenerative therapy. J Periodontol 1993; 64: 1166-70.
  59. Norris LH, Doku HC.  Antimicrobial prophylaxis in oral surgery.  Curr Opin Dent 1992;2:85-92.
  60. Olsen I, Snorrason F, Lingaas E.  Should patients with hip joint prosthesis receive antibiotic prophylaxis before dental treatment?  J Oral Microbiol 2010;2:5265-75.
  61. Oral Health Division Ministry of Health Malaysia.  Clinical practice guidelines on antibiotic prophylaxis in oral surgery for prevention of surgical site infection 2nd ed.  November 2015.
  62. Pallasch TJ, Slots J.  Antibiotic prophylaxis for medical-risk patients.  J Periodontol 1991;62:227-31.
  63. Pallasch TJ.  A critical appraisal of antibiotic prophylaxis.  Int Dent J 1989;39:183-96.
  64. Pallasch TJ.  Antibiotic prophylaxis: theory and reality.  J Calif Dent Assoc 1989;17:27-39.
  65. Piecuch JF, Arzadon J, Lieblich SE.  Prophylactic antibiotics for third molar surgery: a supportive opinion.  J Oral Maxillofac Surg 1995;53:53-60.
  66. Romandini M, De Tullio I, Congedi F, et al.  Antibiotic prophylaxis at dental implant placement: which is the best protocol? A systematic review and network meta-analysis.  J Clin Periodontol. 2019;46:382–95. https://doi.org/10.1111/jcpe.13080.
  67. Rethman MP, Watters W, Abt E, et al.  Prevention of orthopaedic implant infection in patients undergoing dental procedures.  Executive summary on the AAOS/ADA clinical practice guideline.
  68. Sanchez FR,  Andres CR, Arteagoitia I.  Which antibiotic regimen prevents implant failure or infection after dental implant surgery? A systematic review and meta-analysis.  J Cranio-Maxillo-Facial Surg 2018;46:722-36.

  69. Sanchez FR, Arteagoitia I, Teughels W, et al.  Antibiotic dosage prescribed in oral implant surgery: a meta-analysis of cross-sectional surveys.  PLoS ONE 2020;15: e0236981. https://doi.org/10.1371/journal.pone.0236981.

  70. Sancho-Puchades M, Herraez-Vilas JM, Berini-Aytes L, et al.  Antibiotic prophylaxis to prevent local infection in oral surgery:  use or abuse?  Med Oral Patol Oral Cir Bucal 2009;14:E28-33.
  71. Schwartz AB, Larson EL.  Antibiotic prophylaxis and postoperative complications after tooth extraction and implant placement:  a review of the literature.  J Dentistry 2007;35:881-8.
  72. Strom BL, Abrutyn E, Berline JA, et al.  Dental and cardiac risk factors for infective endocarditis: a population-based, case-control study.  Ann Intern Med 1998;129:761-9.
  73. Suda KJ, Henschel H, Patel U, et al.  Use of antibiotic prophylaxis for tooth extractions, dental implants, and periodontal surgical procedures. Open Forum Infect Dis 2017 Nov 15;5(1):ofx250. doi: 10.1093/ofid/ofx250. eCollection 2018 Jan.
  74. Surapaneni H, Yalamanchili PS, Basha MH, et al.  Antibiotics in dental implants:  a review of literature.  J Pharm Bioallied Sci 2016;8:(suppl 1):S28-31.
  75. Swanson AE.  Prevention of dry socket: an overview.  Oral Surg Oral Med Oral Pathol 1990;70:131-6.
  76. Thornhill M.  Amoxicillin is the most effective oral antibiotic prophylaxis regimen for reducing post-invasive dental procedure bacteremia.  J Evid Base Dent Pract 2020: [101464] doi: https://doi.org/10.1016/j.jebdp.2020.101464.
  77. Tong D, Theis JC.  Antibiotic prophylaxis and invasive dental treatment in prosthetic joint patients.  J New Zealand Med Assoc 2008;121:1280-5.
  78. Uyemura MC.  Antibiotic prophylaxis for medical and dental procedures.  Postgrad Med 1995;98:137-152.
  79. Voelker R.  Unnecessary antibiotics.  JAMA 1997;278:620.
  80. Wahl MJ.  Clinical issues in the prevention of dental-induced endocarditis and prosthetic joint infection. Pract Periodontics Aesthet Dent 1995;7:29-37.
  81. Wahl MJ.  Myths of dental-induced prosthetic joint infections.  Clin Infect Dis 1995;20:1420-5.
  82. Walsh LJ.  Serious complications of endodontic infections: some cautionary tales. Aust Dent J 1997; 42: 156-9.
  83. Watters W, Rethman MP, Hanson NB, et al.  AAOS-ADA clinical practice guideline summary.  Prevention of orthopaedic implant infection in patients undergoing dental procedures.  J Am Acad Orthop Surg 2013;21:180-9.
  84. Weitekamp MR, Caputo GM.  Antibiotic prophylaxis: update on common clinical uses.  Amer Fam Phys 1993;48:597-604.
  85. Yagiela JA.  Prophylactic antibiotics: cardiac and prosthetic considerations.  J Calif Dent Assoc 1995;23:29-40.
  86. Young H, Hirsh J, Hammerberg M, et al.  Dental disease and periprosthetic joint infection.  J Bone Joint Surg Am 2014;96:162-8.
  87. Zeitler DL.  Prophylactic antibiotics for third molar surgery: a dissenting opinion.  J Oral Maxillofac Surg 1995;53:61-4.
  88. Zijderveld SA, DDS, Smeele LE, Kostense PJ, et al.  Preoperative antibiotic prophylaxis in orthognathic surgery:  a randomized, double-blind, and placebo-controlled clinical study.  J Oral Maxillofac Surg 1999;57:1403-6.

 

Recommended Empiric Therapy of Selected Dental Infections 

  1. Addy M, Renton-Harper P.  Local and systemic chemotherapy in the management of periodontal disease: an opinion and review of the concept.  J Oral Rehabil 1996;23:219-31.
  2. American Academy of Periodontology.  Statement on Periostat®; 20 mg doxycycline hyclate capsules for oral administration as an adjunct to scaling and root planning for the treatment of adult periodontitis.  https://www.perio.org/resources-products/periostat.htm
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  4. Axelsson P.  Current role of pharmaceutical in prevention of caries and periodontal disease. Int Dent J 1993;43:473-82.
  5. Baker KA, Fotos PG.  The management of odontogenic infections. Dent Clin North Am 1994;38:689-706.
  6. Barr CE.  Practical considerations in the treatment of the HIV-infected patient.  Dent Clin North Am 1994;38:403-23.
  7. Berge TI.  Incidence of large third-molar-associated cystic lesions requiring hospitalization. Acta Odontol Scand 1996;54:327-31.
  8. Blondel-Hill E, Nigrin J.  Guide to antimicrobial susceptibility testing & reporting.  3rd ed.  Dynacare Kasper Medical Laboratories/BC Children's Hospital.  2005.
  9. Bridgeman A, Wiesenfeld D, Newland S.  Anatomical considerations in the diagnosis and management of acute maxillofacial bacterial infections. Aust Dent J 1996;41:238-45.
  10. Broughton RA.  Nonsurgical management of deep neck infections in children. Pediatr Infect Dis J 1992;11:14-8.
  11. Brown KA, Khanafer N, Daneman N, et al. Meta-analysis of antibiotics and the risk of community-associated Clostridium difficile infection. Antimicrob Agents Chemother 2013;57:2326–32. https://doi.org/10.1128/AAC.02176-12
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  21. Edlund C, Bjorkman L, Ekstrand J, et al.  Resistance of the normal human microflora to mercury and antimicrobials after exposure to mercury from dental amalgam fillings. Clin Infect Dis 1996;22:944-50.
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