Legionella spp
Clinical
- Almost always requires valve surgery.
Diagnosis
Blood cultures - requires special blood culture media
Urine for Legionella antigen
Serology
Culture, immunohistology and PCR of surgical material
Optimal duration of therapy unknown; may be up to 5-14 months.
| Therapy | Dose | Duration |
|---|---|---|
| Levofloxacin | 750mg IV/PO daily | ≥ 6 weeks |
| or | ||
| [Erythromycin | 500mg PO/IV q6h | ≥ 6 weeks |
| + | ||
| Rifampin] | 300mg PO bid | ≥ 6 weeks |
Alternative
| Therapy | Dose | Duration |
|---|---|---|
| Doxycycline | 200mg PO bid | ≥ 6 weeks |