NB: Optimal therapy is not established. Linezolid is bacteriostatic; 40% relapse rate.

Daptomycin is bactericidal. Ensure daptomycin MIC < 4µg/mL. Daptomycin monotherapy may not be as efficacious as combination therapy with ampicillin; other agents that may have synergistic activity include rifampin and gentamicin.