Cefepime

Predictable Activity

Aeromonas spp
ß-haemolytic Streptococci (Group A,B,C,G)
Citrobacter koseri
Escherichia coli
Haemophilus influenzae
Haemophilus parainfluenzae
Klebsiella oxytoca
Klebsiella pneumoniae
Moraxella catarrhalis
Neisseria spp
Pasteurella spp
Proteus mirabilis
Pseudomonas aeruginosa
Salmonella spp
Shigella spp
Staphylococcus aureus (MSSA)
Streptococcus pneumoniae (Pen-S, Pen-I)

Unpredictable Activity

Aerobic Gram negative bacilli – nonfermenters
Alcaligenes spp
Citrobacter freundii complex
Comamonas spp
Enterobacter spp
Hafnia spp
Morganella morganii
Proteus vulgaris complex
Providencia spp
Pseudomonas spp (other than P. aeruginosa)
Ralstonia spp
Serratia spp
Shingomonas spp
Staphylococcus lugdunensis
Streptococcus pneumoniae (Pen-R)
Viridans group Streptococci

No/Insufficient Activity

Acinetobacter spp
Actinomyces spp
Anaerobic Gram negative bacilli
Bacillus spp
Bordetella spp
Burkholderia cepacia
Chlamydia spp
Clostridium spp
Corynebacterium spp
Enterobacterales with ESBL or carbapenemase
Enterococcus spp
Listeria monocytogenes
Mycoplasma spp
Rickettsia spp
Staphylococcus aureus (MRSA)
Stenotrophomonas maltophilia