Infants 1 - 3 months
- Consider need for acyclovir if HSV encephalitis possible.
- Tailor antibiotics to C&S results.
Usual Pathogens
Group B Streptococci
E. coli
S. pneumoniae
N. meningitidis
H. influenzae
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 100mg/kg/d IV div q12h | S. pneumoniae - 10-14 days N. meningitidis - 5-7 days H. influenzae - 10 days Group B Strep, Listeria - 2-3 weeks Enterobacterales- ≥ 3 weeks |
| If immunocompromised, add: | ||
| Ampicillin | 300mg/kg/d IV div q6h |