Piperacillin-tazobactam

Predictable Activity

Actinomyces spp
Anaerobes (Gram positive and Gram negative)
ß-haemolytic Streptococci (Group A,B,C,G)
Bacillus spp
Bordetella bronchoseptica
Capnocytophaga spp
Citrobacter koseri
Enterococcus faecalis
Escherichia coli
Haemophilus influenzae
Haemophilus parainfluenzae
Klebsiella oxytoca
Klebsiella pneumoniae
Moraxella catarrhalis
Morganella morganii
Neisseria spp
Pasteurella spp
Proteus mirabilis
Proteus vulgaris complex
Pseudomonas aeruginosa
Raoultella spp
Salmonella spp
Staphylococcus aureus (MSSA)
Streptococcus pneumoniae (Pen-S)

Unpredictable Activity

Acinetobacter spp
Aeromonas spp
Corynebacterium spp
Hafnia spp
Lactobacillus spp
Mycobacterium spp
Pantoea spp
Plesiomonas spp
Providencia spp
Pseudomonas spp (not P. aeruginosa)
Serratia spp
Streptococcus pneumoniae (Pen-I)
Viridans group Streptococci

No/Insufficient Activity

Burkholderia spp
Chlamydia spp
Citrobacter freundii complex
Enterobacter spp
Enterobacterales with ESBL or carbapenemase
Enterococcus faecium
Legionella spp
Listeria monocytogenes
Mycoplasma spp
Nocardia spp
Staphylococcus aureus (MRSA)
Stenotrophomonas maltophilia
Streptococcus pneumoniae (Pen-R)