Oral/odontogenic
Usual Pathogens
Polymicrobial:
Streptococcus spp
H. influenzae
Anaerobes
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Surgical drainage | ||
| + | ||
| Ceftriaxone | 1g IV daily | 14-21 days |
| + | ||
| Metronidazole | 500mg IV q12h | |
| If MRSA risk factors, add: | ||
| Vancomycin | 15mg/kg IV q12h | 14-21 days |
Ceftriaxone allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Levofloxacin | 750mg IV daily | 14-21 days |
| + | ||
| Metronidazole | 500mg IV q12h | |
| If MRSA risk factors, add: | ||
| Vancomycin | 15mg/kg IV q12h | 14-21 days |