Antiviral

Antimicrobial	Paediatric Dose	Cost ($)/Day
acyclovir - HSV	40-60mg/kg/d PO div 2-5x/d	5.40-8.11
acyclovir - VZV	80mg/kg/d PO div 4-5x/d	10.81
acyclovir - HSVE	≤ 3 months:
	60mg/kg/d IV div q8h	245.04
	>3 months-12 y.o.:
	30-45mg/kg/d IV div q8h	122.52-183.78
	≥12 y.o.:
	30mg/kg/d IV div q8h	122.52
acyclovir - VZV immunocompromised	30-60mg/kg/d IV div q8h	122.52-245.04
acyclovir - Neonatal HSV	60mg/kg/d IV div q8h	245.04
valacyclovir	60mg/kg/d PO div q8h	1.49
amantadine	Treatment & Prophylaxis of influenza A ONLY
	1-9 y.o. and/or < 40kg:
	5mg/kg/d PO div bid (max 150mg/day)	1.39
	≥ 10 y.o. and ≥ 40kg:
	100mg PO bid	1.22
oseltamivir	Treatment of influenza A & B
	1-12 y.o.:
	≤ 15kg: 30mg PO bid	3.64
	> 15-23kg: 45mg PO bid	5.46
	> 23-40kg: 60mg PO bid	7.27
	> 40kg: 75mg PO bid	9.09
	≥ 13 y.o.:
	75mg PO bid	6.24
	Prophylaxis of influenza A & B
	1-12 y.o.:
	≤ 15kg: 30mg PO daily	1.82
	> 15-23kg: 45mg PO daily	2.73
	> 23-40kg: 60mg PO daily	3.64
	> 40kg: 75mg PO daily	4.55
	≥ 13 y.o.:
	75mg PO daily	3.12
zanamivir	≥ 7 y.o.:
	Treatment of influenza A & B
	10mg inhaled orally bid	43.53
	Prophylaxis of influenza A & B
	10mg inhaled orally daily	21.77

y.o. = years old
HSV = Herpes simplex virus
HSVE = Herpes simplex virus encephalitis
VZV = Varicella zoster virus