2° to paranasal sinusitis
- Consider P. aeruginosa in recently hospitalized, instrumented, or immunocompromised patients. Use ceftazidime instead of ceftriaxone.
Usual Pathogens
S. pneumoniae
M. catarrhalis
H. influenzae
S. aureus/MRSA
Group A Streptococci
Anaerobes
Paediatric
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 100mg/kg/d IV div q12h | 10-14 days |
| + | ||
| Metronidazole | 30mg/kg/d IV div q8h |
Adult
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cloxacillin | 2g IV q4h | 10-14 days |
| + | ||
| Ceftriaxone | 2g IV q12h | |
| + | ||
| Metronidazole | 500mg IV q8h |