Adults
- Native joints
- +/- non- penetrating trauma
- For chronic monoarticular arthritis, consider mycobacterial infection.
Rare:
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefazolin | 2g IV q8h | 2-4 weeks |
| or | ||
| Cloxacillin | 2g IV q4h | 2-4 weeks |
Penicillin allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefazolin | 2g IV q8h | 2-4 weeks |
Cefazolin allergy/MRSA/IVDU/Immunocompromised/Penetrating Trauma
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 15mg/kg IV q12h | 2-4 weeks |
| + | ||
| Ceftriaxone | 1-2g IV daily |