Fosfomycin IV/PO

NB: Oral fosfomycin is for lower urinary tract infections only.

Predictable Activity

Citrobacter freundii complex
Citrobacter koseri
Escherichia coli
Enterococcus faecalis
Proteus mirabilis

Unpredictable Activity

β-haemolytic Streptococci (Group A,B,C,G)
Enterobacter spp
Enterococcus faecium
Klebsiella spp
Proteus vulgaris complex
Providencia spp
Serratia spp
Staphylococcus aureus (MSSA, MRSA)
Staphylococcus lugdunensis

No/Insufficient Activity

Acinetobacter spp
Aerobic Gram negative bacilli – nonfermenters
Anaerobes
Corynebacterium spp
Haemophilus influenzae
Haemophilus parainfluenzae
Moraxella catarrhalis
Morganella morganii
Neisseria spp
Pseudomonas aeruginosa
Pseudomonas spp
Staphylococcus aureus (VISA)
Staphylococcus saprophyticus
Streptococcus pneumoniae
Viridans group Streptococci