1st line therapy

Usual Pathogen

Helicobacter pylori

Concomitant quadruple therapy

- Success rate 80-85%

Empiric Therapy Dose Duration
[PPI bid 14 days
+    
Amoxicillin 1g PO bid  
+    
Clarithromycin 500mg PO bid  
+    
Metronidazole] 500mg PO bid  

or

Bismuth quadruple therapy

Empiric Therapy Dose Duration
[PPI bid 14 days
+    
Bismuth subsalicylate 2 tabs (524mg) PO qid  
+    
Metronidazole 500mg PO qid  
+    
Tetracycline] 500mg PO qid