Carbapenems
| Antimicrobial | Normal Adult Dose | Dose and Interval Adjustment for Renal Impairment | ||
|---|---|---|---|---|
| Creatinine Clearance (mL/min) | ||||
| >50 | 10 - 50 | <10 (Anuric) | ||
| Ertapenem | 1g IV daily | 1g daily | ≤ 30mL/min: 500mg daily | |
| Imipenem | 500mg IV q6h | q6h | q8-12h | 250-500mg q12h |
| Meropenem | 500mg IV q6h | q6h | 26-50mL/min: q8h | q24h |
| 10-25mL/min: q12h | ||||
| 1-2g IV q8h | q8h | q12h | 500mg q24h | |