Post-Trauma
- Fulminant onset 2-7 days following penetrating trauma.
- Vitrectomy may be required.
- Consider adjunctive systemic antibiotics.
- Intravitreal dexamethasone 0.4mg/0.1mL may be beneficial.
Usual Pathogens
Bacillus cereus
Coagulase-negative Staphylococcus
Enterobacterales
Pseudomonas spp
Anaerobes
Fungi
Ophthalmic Preparations
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin 1mg/0.1mL | 0.1mL intravitreally | Dependent on clinical picture |
| + | ||
| Ceftazidime 2.25mg/0.1mL | 0.1mL intravitreally |
ß-lactam Allergy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin 1mg/0.1mL | 0.1mL intravitreally | Dependent on clinical picture |
| + | ||
| [Gentamicin 0.2mg/0.1mL | 0.1mL intravitreally | |
| or | ||
| Amikacin 0.4mg/0.1mL] | 0.1mL intravitreally |