Cellulitis/abscess - unresponsive risk factors

- If severe infection or unresponsive to above suggested empiric therapy, assess for the following risk factors and modify empiric therapy to cover those specific pathogens.

 

Condition Other Potential Pathogens
Diabetic wound/ulcer Group B Streptococci
If chronic:

Anaerobes

Enterobacterales

Neutropenia Pseudomonas aeruginosa
Cirrhosis

Capnocytophaga canimorsus (if animal exposure)

Enterobacterales
Vibrio vulnificus (hemorrhagic bullous lesions) if salt water exposure
Campylobacter fetus

Intravenous drug use MRSA
Pseudomonas aeruginosa
Subcutaneous drug use Eikenella corrodens
Streptococcus anginosus group
Anaerobes
Fresh water exposure Aeromonas hydrophila complex
Salt water exposure Vibrio spp
Post trauma with soil/water exposure, cosmetic procedures, recreational water sports Mycobacterium spp
Send specimen for mycobacterial culture
Fish tank exposure, fisherman Mycobacterium marinum
Send specimen for mycobacterial culture
Reptile contact Salmonella spp