Mild-moderate, non-hospitalized

- Test and treat, regardless of clinical signs/symptoms, all recent (60 days) sexual contacts.

- PID is not an indication for IUD removal.  If IUD removal is planned however, delay removal until at least two doses of antibiotics have been administered.

 
Usual Pathogens

N. gonorrhoeae
C. trachomatis

Mycoplasmoides genitalium (previously Mycoplasma genitalium)

 
Polymicrobial:

Enterobacterales
Anaerobes
Streptococcus spp
Haemophilus spp
Gardnerella vaginalis

Rare:

Herpes simplex virus
Trichomonas vaginalis

 

Empiric Therapy Dose Duration
Ceftriaxone 250mg IM 1 dose
+    
Doxycycline 100mg PO bid 14 days
+/-    
Metronidazole 500mg PO bid 14 days

Ceftriaxone allergy

Empiric Therapy Dose Duration
Levofloxacin 500mg PO daily 14 days
+/-    
Metronidazole 500mg PO bid 14 days