HIV
Toxoplasma gondii
Consult Infectious Diseases.
| Empiric Therapy | Dose | Duration |
|---|---|---|
| TMP/SMX alone | 5mg TMP/kg PO/IV q12h | Minimum 6 weeks after signs/ symptoms resolved |
| or | ||
| [Pyrimethamine | 200mg PO loading dose then 50mg (if <60kg) or 75mg (if ≥60kg) PO daily | Minimum 6 weeks after signs/ symptoms resolved |
| + | ||
| Folinic acid | 10-25mg PO daily | |
| + | ||
| Sulfadiazine ] | 1g (if <60kg) or 1.5g (if ≥60kg) PO q6h |
Then follow with suppressive therapy
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Pyrimethamine | 25-50mg PO daily | Discontinue if CD4 count > 200 x 6 months |
| + | ||
| Folinic acid | 10-25mg PO daily | |
| + | ||
| [Sulfadiazine | 0.5-1g PO q6h | |
| or | ||
| Clindamycin] | 600mg PO q8h | |
| or | ||
| Atovaquone alone | 750mg PO q6-12h | Discontinue if CD4 count > 200 x 6 months |