Involving trunk, neck, head, extremity
Usual PathogensS. aureus/MRSA
Group A Streptococci
Mild (< 5cm erythema/induration)
- Temp ≤ 38.5 ºC and pulse ≤ 110/min:
Local management
Antibiotics not generally recommended unless significant underlying conditions, e.g. obesity, wound overlying joint, immunosuppression.
- Temp > 38.5ºC or pulse > 110/min or WBC >12 x 109/L:
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cephalexin | 500-1000mg PO qid | 24-48 hours |
Cephalexin allergy
| Empiric Therapy | Duration | |
|---|---|---|
| Cefuroxime axetil | 500mg PO bid | 24-48 hours |
Cefuroxime allergy
| Empiric Therapy | Duration | |
|---|---|---|
| Clindamycin | 300mg PO qid | 24-48 hours |
Moderate-severe
| Empiric Therapy | Duration | |
|---|---|---|
| Cefazolin | 2g IV q8h | 5-10 days |
Cefazolin allergy
| Empiric Therapy | Duration | |
|---|---|---|
| Ceftriaxone | 2g IV daily | 5-10 days |
Ceftriaxone allergy
| Empiric Therapy | Duration | |
|---|---|---|
| Vancomycin | 15mg/kg IV q12h | 5-10 days |