Post-partum

- Encourage milk flow from affected breast either through breast feeding or breast pump.

- Risk factors for abscess formation:

  • maternal age > 30 years

  • gestational age > 41 weeks

  • history of mastitis

- Can continue breast-feeding while on therapy.

- Consider ultrasound if no response after one course of antibiotics.

 
Usual Pathogens

S. aureus

Minimal symptoms

Empiric Therapy

Dose

Duration
Hot compresses    

 

Mild

Empiric Therapy

Dose

Duration
Cloxacillin 500mg PO qid 7-10 days
or    
Cephalexin 500-1000mg PO qid 7-10 days

Penicillin and cephalexin allergy

Empiric Therapy Dose Duration
Cefuroxime axetil 500mg PO bid 7-10 days

Cefuroxime allergy/MRSA

Empiric Therapy Dose Duration
Clindamycin 300mg PO qid 7-10 days

 

Moderate-severe

Empiric Therapy

Dose

Duration
Cloxacillin 2g IV q6h 7-10 days
or    
Cefazolin 2g IV q8h 7-10 days

Penicillin and cefazolin allergy

Empiric Therapy Dose Duration
Ceftriaxone 2g IV daily 7-10 days

Ceftriaxone allergy/MRSA

Empiric Therapy

Dose

Duration
Vancomycin 15mg/kg IV q12h 7-10 days