Streptococci spp

Including:

S. pyogenes
S. agalactiae
Streptococcus Group C&G

Streptococcus anginosus group
Streptococcus bovis group
Streptococcus viridans group

S. pneumoniae

 

Therapy Dose Duration
Penicillin 4MU IV q4h

One- or two-stage exchange:  4-6 weeks

Debridement and implant retention (DAIR):  12 weeks

or    
Ceftriaxone

1-2g IV daily

One- or two-stage exchange:  4-6 weeks

Debridement and implant retention (DAIR):  12 weeks

Penicillin and ceftriaxone allergy

Therapy Dose Duration
Vancomycin 15mg/kg IV q12h

One- or two-stage exchange:  4-6 weeks

Debridement and implant retention (DAIR):  12 weeks

or    
Clindamycin 450mg PO qid

One- or two-stage exchange:  4-6 weeks

Debridement and implant retention (DAIR):  12 weeks