Antituberculous Agents
| Antimicrobial | Normal Adult Dose | Dose and Interval Adjustment for Renal Impairment | ||
|---|---|---|---|---|
| Creatinine Clearance (mL/min) | ||||
| >30 | 10 - 30 | <10 (Anuric) | ||
| Ethambutol | 15-25 mg/kg PO daily or 5x/week | NO CHANGE NEEDED | 3 times per week | 3 times per week |
| Isoniazid | 5mg/kg PO daily or 5x/week | NO CHANGE NEEDED | ||
| Pyrazinamide | 20-30 mg/kg PO daily or 5x/week | NO CHANGE NEEDED | 3 times per week | 3 times per week |
| Rifampin | 10mg/kg PO daily or 5x/week | NO CHANGE NEEDED | ||