Haemophilus influenzae

Amoxicillin-susceptible

Therapy Dose Duration
Amoxicillin 1g PO tid 5 days

Amoxicillin-resistant, ß-lactamase positive

Therapy Dose Duration
Amoxicillin-clavulanate 875mg PO bid 5 days
or    
TMP/SMX (if susceptible)

1 DS tab PO bid/10mg TMP/kg/d

IV div q12h

5 days
or    
Ceftriaxone 1g IV daily 5 days

Amoxicillin-resistant, ß-lactamase negative

Therapy Dose Duration
TMP/SMX (if susceptible) 1 DS tab PO bid/10mg TMP/kg/d IV div q12h 5 days
or    
Ceftriaxone 1-2g IV daily 5 days
or    
Levofloxacin 750mg IV/PO daily 5 days