Protozoan

- Risk factors:

  • trauma
  • soft contact lens use (overnight use increases risk).

- Severe pain is a predominant symptom.

- Consult ophthalmology and microbiology for diagnosis.

 
Usual Pathogens

Acanthamoeba spp

Ophthalmic Solutions

Empiric Therapy Dose Duration
Propamidine 0.1% q1h while awake, then slowly reduce frequency Dependent on clinical picture
+    
[Polyhexamethylene biguanide 0.02% q1h while awake, then slowly reduce frequency  
and/or    
Chlorhexidine 0.02%] q1h while awake, then slowly reduce frequency  
+/-    
Neomycin-gramicidin-polymyxin B q1h while awake, then slowly reduce frequency