Mild-moderate

- Self-limiting. Usual duration of diarrhea 3-5 days.

- Persistent diarrhea suggests protozoal causes: Giardia, Cryptosporidium, Cyclospora, Entamoeba histolytica, Microsporidia. See Treatment of Enteric Parasitic Infections.

 
Usual Pathogens

diarrheagenic E. coli
Campylobacter spp
Shigella spp
Salmonella spp

 

Empiric Therapy Dose Duration
Fluid replacement    
+    
Bismuth subsalicylate 2 x 262 mg tabs chewed well q30-60 minutes  No more than 8 doses/day
+/-    
Antimotility agents (e.g. loperamide)

4mg PO x 1 dose, then

2mg after each loose stool

Max 16mg/day for no more than 2 days