Pregnancy

- Pre/1-week post treatment urine cultures recommended followed by monthly follow-up cultures during remainder of pregnancy.

- Tailor antibiotics to C&S results.

- Based on clinical response, switch to oral agent(s) as listed under Uncomplicated pyelonephritis and/or according to C&S results.

 
Usual Pathogens

E. coli
Other Enterobacterales
S. agalactiae (Group B Strep)

 

Empiric Therapy Dose Duration
Ceftriaxone 1-2g IV q24h 7 days

Alternative

Empiric Therapy Dose Duration
Gentamicin 7mg/kg IV q24h 7 days
+    
Ampicillin 2g IV q6h