Cutibacterium acnes
| Therapy | Duration | |
|---|---|---|
| Penicillin G | 4MU IV q4h |
10 days if no or minimal CSF pleocytosis, normal CSF glucose, and few clinical symptoms or systemic features. 10-14 days if significant CSF pleocytosis, low CSF glucose, or clinical symptoms or systemic features. |
Alternative
| Therapy | Duration | |
|---|---|---|
| Ceftriaxone | 2g IV q12h |
10 days if no or minimal CSF pleocytosis, normal CSF glucose, and few clinical symptoms or systemic features. 10-14 days if significant CSF pleocytosis, low CSF glucose, or clinical symptoms or systemic features. |
Penicillin and ceftriaxone allergy
| Therapy | Duration | |
|---|---|---|
| Vancomycin | 15mg/kg IV q8-12h |
10 days if no or minimal CSF pleocytosis, normal CSF glucose, and few clinical symptoms or systemic features. 10-14 days if significant CSF pleocytosis, low CSF glucose, or clinical symptoms or systemic features. |