Anaerobic Gram positive bacilli (other)

• Adlercreutzia spp
• Alloscardovia spp
• Anaerofustis spp
• Anaerostipes spp
• Anaerotruncus spp
• Atopobium spp
• Bifidobacterium spp
• Bulleidia spp
• Catabacter spp
• Cateribacterium spp
• Collinsella spp
• Cryptobacterium spp
• Dorea spp
• Eggerthella spp
• Eubacterium spp
• Faecalibacterium spp
• Filifactor spp
• Flavonifractor spp
• Gordonibacter spp
• Hjoldemania spp
• Marvinbryantia spp
• Mobiluncus spp
• Mogibacterium spp
• Olsenella spp
• Oribacterium spp
• Paraeggerthella spp
• Parascardovia spp
• Propioniferax spp
• Propionimicrobium spp.
• Pseudoramibacter spp
• Robinsonella spp
• Roseburia spp
• Scardopvia spp
• Shuttleworthia spp
• Slackia spp
• Solobacterium spp
• Turicibacter spp
• Varibaculum spp

Clinical Significance

These organisms are part of the normal flora of the upper respiratory, skin, genitourinary, and gastrointestinal tracts. 

Although of low pathogenicity, they have been found in polymicrobial infections including wound infections and genitourinary tract infections (including intrauterine contraceptive related pelvic infections). 

They rarely are isolated in bacteremia but have been reported in endocarditis, pleuropulmonary infections, breast and brain abscesses, meningitis, and peritonitis.

They have sometimes been found in urine specimens where they may have a pathogenic role  (Alloscardovia spp).

Usual Susceptibility Pattern

These organisms are usually susceptible to penicillin, clindamycin, vancomycin, and carbapenems.  Although Eggerthella spp exhibits high rates of resistance to both penicillin and piperacillin-tazobactam.

Susceptibility to clindamycin and metronidazole is variable.

Metronidazole resistance has been reported in Alloscardovia, Atopobium, Bifidobacterium, Eggerthella, Eubacterium, and Mobiluncus spp.

Alloscardovia spp (occasional uropathogen) is resistant to fosfomycin and nitrofurantoin.